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Invitrogen

Sodium Potassium ATPase Recombinant Rabbit Monoclonal Antibody (3L6F0)

View all (2) Sodium Potassium ATPase antibodies
Datasheet
Protocols
Questions & Answers
Tech Support
Datasheet
Protocols
Questions & Answers
Tech Support

Product Details

MA5-42645

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500 - 1:2,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:50 - 1:200
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

3L6F0

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Na+/K+-ATPase (P05023).
View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.72 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

RRID

AB_2911786

Product Specific Information

Positive test controls include: HeLa, 293T, Mouse Liver. The target is usually found in the following locations: Cell membrane, Melanosome, Multi-pass membrane protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ATPase, Na+/K+ transporting, alpha 1 polypeptide; ATPase, Na+/K+ transporting, alpha 4 polypeptide; ATPase, Na+/K+ transporting, alpha polypeptide-like 2; ATPase, Na+K+ transporting, alpha 1; Na(+)/K(+) ATPase alpha-1 subunit; Na(+)/K(+) ATPase alpha-4 subunit; Na+/K+ ATPase 1; Na+/K+ ATPase 4; Na+/K+ ATPase alpha 4 subunit; Na+/K+ ATPase, alpha-D polypeptide; Na, K-ATPase, alpha-A catalytic polypeptide; Na,K-ATPase alpha-1 subunit; Na,K-ATPase catalytic subunit alpha-A protein; Na,K-ATPase subunit alpha-C; sodium pump 4; Sodium pump subunit alpha-1; Sodium pump subunit alpha-4; sodium-potassium ATPase catalytic subunit alpha-1; sodium-potassium ATPase catalytic subunit alpha-4; sodium-potassium-ATPase, alpha 1 polypeptide; sodium/potassium-transporting ATPase alpha-4 chain; Sodium/potassium-transporting ATPase subunit alpha-1; Sodium/potassium-transporting ATPase subunit alpha-4

Gene Aliases: ATP1A1; ATP1A4; ATP1AL2; Atpa-1; BC010319; Nkaa1b

UniProt ID: (Human) P05023, (Human) Q13733, (Rat) P06685, (Mouse) Q8VDN2, (Mouse) Q9WV27, (Rat) Q64541

Entrez Gene ID: (Human) 476, (Human) 480, (Rat) 24211, (Mouse) 11928, (Mouse) 27222, (Rat) 29132

Molecular Function: primary active transporter

Function(s)
regulation of the force of heart contraction regulation of sodium ion transport cellular sodium ion homeostasis regulation of blood pressure potassium ion import establishment or maintenance of transmembrane electrochemical gradient ATP hydrolysis coupled proton transport dephosphorylation cellular potassium ion homeostasis negative regulation of glucocorticoid biosynthetic process ion transmembrane transport sodium ion export from cell response to drug negative regulation of heart contraction positive regulation of heart contraction positive regulation of striated muscle contraction relaxation of cardiac muscle cardiac muscle contraction membrane hyperpolarization cellular response to mechanical stimulus cellular response to steroid hormone stimulus regulation of cardiac muscle cell contraction membrane repolarization membrane repolarization during cardiac muscle cell action potential cell communication by electrical coupling involved in cardiac conduction response to glycoside regulation of cardiac conduction potassium ion import across plasma membrane potassium ion transport sodium ion transport spermatogenesis fertilization sperm motility regulation of cellular pH regulation of membrane potential energy coupled proton transmembrane transport, against electrochemical gradient sodium ion transmembrane transport potassium ion transmembrane transport transport ion transport metabolic process
Process(es)
sodium:potassium-exchanging ATPase activity protein binding ATP binding phosphatase activity protein kinase binding protein domain specific binding ankyrin binding potassium ion binding sodium ion binding ADP binding phosphatidylinositol 3-kinase binding chaperone binding steroid hormone binding metal ion binding nucleotide binding hydrolase activity
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