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|Tested species reactivity||Human|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic cyclic (1-14) somatostatin|
|Storage buffer||whole serum diluted in PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-16253 targets Somatostatin in IHC (P) applications and shows reactivity with Human samples.
The PA5-16253 immunogen is synthetic cyclic (1-14) somatostatin.
The cyclic polypeptide hormone Somatostatin was originally isolated from the hypothalamus and characterized by its ability to inhibit release of growth hormone from the pituitary gland. It exists in two forms, somatostatin-14, composed of 14 amino acids and somatostatin-28, a prohormone composed of 28 residues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Promoter hypermethylation-related reduced somatostatin production promotes uncontrolled cell proliferation in colorectal cancer.
PA5-16253 was used in immunohistochemistry - paraffin section to analyze promotion of uncontrolled cell proliferation in colorectal cancer by promoter hypermethylation-related somatostatin production
|Leiszter K,Sipos F,Galamb O,Krenács T,Veres G,Wichmann B,F¿ri I,Kalmár A,Patai ÁV,Tóth K,Valcz G,Tulassay Z,Molnár B||PloS one (10:null)||2015|
Targeted multiplex imaging mass spectrometry in transmission geometry for subcellular spatial resolution.
PA5-16253 was used in immunohistochemistry to develop a mass spectroscopic methodology for the targeted imaging of single cells within a tissue
|Thiery-Lavenant G,Zavalin AI,Caprioli RM||Journal of the American Society for Mass Spectrometry (24:609)||2013|
Growth hormone release-inhibiting factor; prepro-somatostatin; Somatostatin; somatostatin-14; somatostatin-28