Sorbitol dehydrogenase catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NADcofactor.
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Protein Aliases: (R,R)-butanediol dehydrogenase; epididymis secretory sperm binding protein Li 95n; L-iditol 2-dehydrogenase; Polyol dehydrogenase; RDH; Ribitol dehydrogenase; SDH; Sorbitol dehydrogenase; sorbitol dehydrogenase 1; SORD 1; XDH; Xylitol dehydrogenase
Gene Aliases: HEL-S-95n; Sdh-1; Sdh1; Sodh-1; SORD; SORD1
Molecular Function: dehydrogenase