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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG1|
|Immunogen||Synthetic peptide mapping to the carboxy terminus of human Sp3.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:200|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-30616 detects Sp3 from mouse, rat, human samples.
PA1-30616 has been successfully used in Western blot applications.
The PA1-30616 immunogen is: Synthetic peptide mapping to the carboxy terminus of human Sp3.
This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DKFZp686O1631; GC-binding transcription factor Sp3; specificity protein 3; SPR-2; SPR2; trans-acting transcription factor 3; Transcription factor Sp3
D130027J01Rik; SP3; SPR2