|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||5-10 µg/ml|
|Western Blot (WB)||See 1 publications below|
|Tested Species reactivity||Human, Mouse|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to human sphingomyelin synthase 1.|
|Storage buffer||PBS, pH 7.4|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
A suggested positive control for this product is brain, heart, kidney, liver, muscle or stomach lysate.
A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hmob33; Medulla oblongata-derived protein; MGC17342; MOB; MOB1; Phosphatidylcholine:ceramide cholinephosphotransferase 1; Protein Mob; SMS1; Sphingomyelin synthase 1; TMEM23; Transmembrane protein 23
Gene Aliases: 9530058O11Rik; AI841905; C80702; hmob33; MOB; MOB1; SGMS1; SMS1; Sor1; TMEM23
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