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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 395 of Human Squalene synthetase(SQS)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-28912 targets Squalene synthetase(SQS) in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28912 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 395 of Human Squalene synthetase(SQS).
This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
DGPT; ERG9; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; squalene synthase; squalene synthetase; SS
DGPT; ERG9; FDFT1; SQS; SS