Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
1 µg/mL of MA5-27645 was sufficient for detection of TARP Gamma2/4/8 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.|Detects approximately 35-55kDa. Does not cross-react with TARPGamma3.
This antibody was formerly sold as clone S245-36.
Stargazin is a member of the transmembrane AMPAR regulatory proteins (TARP) family and is involved in glutamate receptor trafficking. It has been recently demonstrated that the interaction between stargazin and AMPA receptors is critical for the correct localization of the receptors at the synapse. Phosphorylation of the stargazin protein at Thr 321 by Protein Kinase A regulates its interaction with PSD-95 and synaptic targeting of AMPA receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: calcium channel, voltage-dependent, gamma subunit 2; CaV gamma 2; MGC123981; MGC138502; MGC138504; Neuronal voltage-gated calcium channel gamma-2 subunit; Stargazin; TARP gamma 2; TARP gamma-2; Transmembrane AMPAR regulatory protein gamma-2; Voltage-dependent calcium channel gamma-2 subunit
Gene Aliases: AW060990; B230105C07Rik; B930041E13Rik; CACNG2; Ipr328; MRD10; stargazer; stargazin; Stg; wag; waggler
UniProt ID: (Human) Q9Y698, (Rat) Q71RJ2, (Mouse) O88602
Entrez Gene ID: (Human) 10369, (Rat) 84347, (Mouse) 12300
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