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|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide corresponding to residues 200-300 of an internal portion of human Striatin 3. [Swiss-Prot# Q13033]|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:250-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
SG2NA was identified as a human cancer autoantigen and has now been implicated in vesicular trafficking and signal transduction. It is highly related to striatin and zinedin. It is a scaffolding protein that binds PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which has been implicated in control of mitotic progression in yeast. It also binds calmodulin and appears to modulate PP2A activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Tissue specific expression of SG2NA is regulated by differential splicing, RNA editing and differential polyadenylation.
MA1-46461 was used in western blot to examine the different splice variants of SG2NA during cell differentiation
|Jain BP,Chauhan P,Tanti GK,Singarapu N,Ghaskadbi S,Goswami SK||Gene (556:119)||2015|
cell cycle autoantigen SG2NA; cell cycle S/G2 nuclear autoantigen; Cell-cycle autoantigen SG2NA; GS2NA; nuclear autoantigen; protein phosphatase 2 regulatory subunit B'''beta; s/G2 antigen; SG2NA; SG2NA beta isoform; striatin, calmodulin binding protein 3; striatin-3; striatin-3 35 kDa; striatin-3-gamma; STRN3
GS2NA; PPP2R6B; SG2NA; STRN3