|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Not Applicable|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide made to an internal portion of the human Striatin protein (within residues 350-400). [Swiss-Prot# O43815]|
|Storage buffer||whole serum|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Western Blot (WB)||See 1 publications below|
Suggested positive control: antigen standard for STRN (transient overexpression lysate).
This antibody specific for Striatin. It does not cross-react with SG2NA.
Striatin is found in all mammalian cells assayed and may be involved in vesicular transport, dendrite growth, and cellular signaling. It binds Protein phosphatase 2A (PP2A) A and C subunits and calmodulin and appears to modulate PP2A activity. It also binds the human homolog of the yeast protein, Mob1, which has been implicated in mitotic progression in yeast. It is a member of a family of proteins that also includes SG2NA and Zinedin. This antibody does not cross-react with SG2NA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers.
PA1-46460 was used in western blot to determine the function of greatwall-phosphorylated endosulfine as a substrate of PP2A-B55 heterotrimers and an inhibitor
|Williams BC,Filter JJ,Blake-Hodek KA,Wadzinski BE,Fuda NJ,Shalloway D,Goldberg ML||eLife (3:null)||2014|