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|Tested species reactivity||Human, Mouse, Rat|
|Published species reactivity||Rat, Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues surrounding cysteine 60 of human Survivin|
|Storage buffer||0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/ml BSA, 50% glycerol|
|Contains||<0.02% sodium azide|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:400|
|Immunohistochemistry (Frozen) (IHC (F))||1:400|
|Immunohistochemistry (Paraffin) (IHC (P))||1:400|
|Western Blot (WB)||1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
It is not recommended to aliquot this antibody.
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Therapeutic potential of cannabidiol against ischemia/reperfusion liver injury in rats.
MA5-15077 was used in immunohistochemistry to investigate the therapeutic potential of cannabidiol against rodent hypoxia-reoxygenation injury
|Fouad AA,Jresat I||European journal of pharmacology (670:216)||2011|
Expression of survivin, CD117, and C-erbB-2 in neuroendocrine carcinoma of the uterine cervix.
MA5-15077 was used in immunohistochemistry to identify the relationship between protein expression and prognosis in carcinomas
|Sukpan K,Settakorn J,Khunamornpong S,Cheewakriangkrai C,Srisomboon J,Siriaunkgul S||International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (21:911)||2011|
apoptosis inhibitor 4; apoptosis inhibitor survivin; baculoviral IAP repeat-containing protein 5; survivin; survivin variant 3 alpha
AAC-11; AP14; API4; BIRC5; EPR-1; IAP4; survivin40; TIAP