Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
PA1-4977 detects Swi6 from S. pombe samples.
PA1-4977 has been successfully used in Western blot and immunoprecimmunoprecipitationitation applications. Western blot analysis of crude extract of S. pombe detects a protein with an apparent molecular size of 53 kD.
Swi6 protein of fission yeast is a functional and structural homolog of HP1 (Heterochromatin Protein 1) of animals and is involved in the formation of heterochromatin structure by binding to centromere, telomere and silent mating-type locus. It is also involved in silencing the genes and sister chromatid cohesion by binding to histone H3 methylated at Lys9 and the cohesin subunit Psc3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell-cycle box factor subunit SWI6; MBF subunit P90; Regulatory protein SWI6; Trans-acting activator of HO endonuclease gene
Gene Aliases: L9470.8; PSL8; SDS11; SWI6; YLR182W
Entrez Gene ID: (Baker's yeast) 850879
Molecular Function: hydrolase
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