Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:1,000-1:1,500 | - |
Immunohistochemistry (IHC) |
- | View 1 publication 1 publication |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:100-1:500 | - |
Immunohistochemistry (PFA fixed) (IHC (PFA)) |
Assay-dependent | - |
Immunohistochemistry (Frozen) (IHC (F)) |
1:100-1:500 | - |
Immunocytochemistry (ICC/IF) |
- | View 1 publication 1 publication |
Flow Cytometry (Flow) |
1:200-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Bovine, Human, Mouse, Rat |
Published species |
Not Applicable |
Host/Isotype |
Mouse / IgG1 |
Class |
Monoclonal |
Type |
Antibody |
Clone |
SY38 |
Immunogen |
Synaptophysin from presynaptic vesicles from bovine brain |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS |
Contains |
0.05% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2723681 |
MA1-213 has been successfully used in western blot, imunofluorescence, immunohistochemistry, flow cytometry, immunoprecipitation and ELISA.
MA1-213 detects Synaptophysin in human, bovine, mouse and rat samples.
Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis. It is also involved in the regulation of short-term and long-term synaptic plasticity. Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors. Mutations in the gene can result in mental retardation, X-linked 96.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: BM89 antigen; Major synaptic vesicle protein p38; Synaptophysin; Syp I
Gene Aliases: A230093K24Rik; AI848995; MRX96; MRXSYP; p38; Syn; SYP; Syp1
UniProt ID: (Human) P08247, (Bovine) P20488, (Rat) P07825, (Mouse) Q62277
Entrez Gene ID: (Human) 6855, (Bovine) 280937, (Rat) 24804, (Mouse) 20977
Molecular Function:
membrane trafficking regulatory protein
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