|Tested species reactivity||Human, Rat|
|Published species reactivity||Non-human primate, Human|
|Host / Isotype||Mouse / IgG1, kappa|
|Storage buffer||tissue culture supernatant|
|Contains||0.09% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:2|
|Immunohistochemistry (Paraffin) (IHC (P))||1:10-1:20|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||1:100-1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 6 publications below|
MA5-12400 targets CD138 in IHC (P), FACS, IP, and WB applications and shows reactivity with Human and Rat samples.
The MA5-12400 immunogen is u-266 cells.
CD138/Syndecan-1 is a transmembrane heparin sulphate proteoglycan which is made up of one core protein and five glycosaminoglycan. CD138 is expected to play a role in cell adhesion. It is expressed on the surface of pre-B cells and plasma cells but is absent from mature B cells. It is a selective marker for B cell lymphoblastic leukemia and lymphoplasmocytoid leukemia. It is lost from the apoptotic myeloma cells; hence, it is a useful marker for viable myeloma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Non-human primate||Not Cited||
Activated B cells in the granulomas of nonhuman primates infected with Mycobacterium tuberculosis.
MA5-12400 was used in immunohistochemistry to study the presence of active B-cells in granulomas of monkeys infected with Mycobacterium tuberculosis
|Phuah JY,Mattila JT,Lin PL,Flynn JL||The American journal of pathology (181:508)||2012|
EBV+ diffuse large B-cell lymphoma arising within atrial myxoma. An example of a distinct primary cardiac EBV+ DLBCL of immunocompetent patients.
MA5-12400 was used in immunohistochemistry to report on a case of EBV+ diffuse large B-cell lymphoma arising within atrial myxoma
|Svec A,Rangaiah M,Giles M,Jaksa R,McAulay KA||Pathology, research and practice (208:172)||2012|
Primary myoepithelial carcinoma of the larynx: case report and review of the literature.
MA5-12400 was used in immunohistochemistry to report on a case of primary myoepithelial carcinoma of the larynx
|Yu G,Qu G,Kong L,Pan X,Wang W,Lv J||Pathology, research and practice (207:127)||2011|
An immunohistochemical study of colon adenomas and carcinomas: E-cadherin, Syndecan-1, Ets-1.
MA5-12400 was used in immunohistochemistry to investigate the immunohistochemical differences between colon adenomas and carcinomas
|Pap Z,Pávai Z,Dénes L,Kovalszky I,Jung J||Pathology oncology research : POR (15:579)||2009|
Local immune alterations in oral mucosa of the edentulous patients; possible cause of teeth loss?
MA5-12400 was used in immunohistochemistry to investigate immune cells of oral mucosa derived from edentulous patients
|Zurac S,Girtan M,Lavric L,Petsakos G,St¿niceanu F,Bastian A,Andrei R,Popp C,Laba E||Romanian journal of internal medicine = Revue roumaine de medecine interne (46:249)||2009|
Differences in the tumor microenvironment between African-American and European-American breast cancer patients.
MA5-12400 was used in immunohistochemistry to compare tumor microenvironments between African-American and European-American breast cancer patients
|Martin DN,Boersma BJ,Yi M,Reimers M,Howe TM,Yfantis HG,Tsai YC,Williams EH,Lee DH,Stephens RM,Weissman AM,Ambs S||PloS one (4:null)||2009|