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Syntrophin alpha-1 (Dystrophin, SNTA1) is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
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Protein Aliases: 59 kDa dystrophin-associated protein A1 acidic component 1; acidic alpha 1 syntrophin; Alpha-1-syntrophin; alpha1-syntrophin; dystrophin-associated protein A1, 59kDa, acidic component; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; RP23-192L3.1; syntrophin, acidic 1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); Syntrophin-1; TACIP1
Gene Aliases: AW228934; dJ1187J4.5; LQT12; SNT1; SNTA1; TACIP1
UniProt ID: (Human) Q13424
Entrez Gene ID: (Human) 6640, (Mouse) 20648, (Rat) 362242
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