|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (DSQSLARKYMYSS) corresponding to the C-terminus amino acids of SNTG2|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: G2SYN; Gamma-2-syntrophin; gamma2-syntrophin; MGC133174; SNTG2; SYN5; syntrophin 5; syntrophin 5 gamma2-syntrophin; syntrophin, gamma 2; Syntrophin-5
Gene Aliases: G2SYN; SNTG2; SYN5
UniProt ID: (Human) Q9NY99
Entrez Gene ID: (Human) 54221
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