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|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 180 of Human TAF148|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:3000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA5-31155 targets TAF148 in WB applications and shows reactivity with Human samples.
The PA5-31155 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 180 of Human TAF148.
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
48kD subunit; MGC:17061; RAFI48; RNA polymerase I-specific TBP-associated factor 48 kDa; SL1; SL1, 48kD subunit; TAFI48; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; TATA box binding protein associated factor 1A; TATA box-binding protein-associated factor 1A; TATA-box binding protein associated factor, RNA polymerase I, A; TBP-associated factor 1A; transcription factor SL1; transcription in; transcription initiation factor SL1/TIF-IB subunit A
MGC:17061; RAFI48; SL1; TAF1A; TAFI48