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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Purification||Ion-exchange chromatography, Ammonium sulfate precipitation|
|Storage buffer||50% water with 50% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||5-10 µg/mL|
|Inhibition Assays (IA)||Assay Dependent.|
|Western Blot (WB)||5 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-43023 detects TAFI in human samples.
MA1-43023 has successfully been used in Western Blot, ELISA, and Inhibition Assay applications.
MA1-43023 was derived from human TAFI and activated TAFI.
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The TAFI protein is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
carboxypeptidase B-like protein; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase R; CPB2; PCPB; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
CPB2; CPU; PCPB; TAFI