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|Tested species reactivity||Human|
|Host / Isotype||Sheep / IgG|
|Immunogen||Purified Human TAFI.|
|Purification||Ammonium sulfate precipitation, Ion-exchange chromatography|
|Storage buffer||50% water with 50% glycerol|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||10 µg/ml|
|Western Blot (WB)||10 ug/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-43056 detects TAFI in human samples.
PA1-43056 has successfully been used in Western blot and ELISA applications.
PA1-43056 was derived from purified human TAFI.
Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The TAFI protein is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
carboxypeptidase B-like protein; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase R; CPB2; PCPB; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
CPB2; CPU; PCPB; TAFI