Immunogen sequence: PAEIAGLQIGD KIMQVNGWDM TMVTHDQARK RLTKRSEEVV RLLVTRQSLQ KAVQQSMLS
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.
Protein Aliases: C20orf100; GCX1; Glutaminase-interacting protein 3; Tax interaction protein 1; Tax-interacting protein 1; Tax1 (human T-cell leukemia virus type I) binding protein 3; Tax1-binding protein 3; TAX1BP3; TIP-1
Gene Aliases: TAX1BP3; TIP-1; TIP1
UniProt ID: (Human) O14907
Entrez Gene ID: (Human) 30851