|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Human TAZ protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 15% glycerol|
|Contains||0.02% sodium azide|
|Storage Conditions||-20°C or -80°C if preferred|
|Tested Applications||Dilution *|
|ChIP assay (ChIP)||Assay-Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay-Dependent|
|Western Blot (WB)||1:1000-1:5000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: 293 whole cell lysate, antigen standard for WWTR1 (transient overexpression lysate), HEK 293 lysate and kidney tissue lysate, human kidney protein.
Highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. A novel transcriptional co-activator, TAZ (transcriptional co-activator with PDZ-binding motif) functions as a 14-3-3-binding molecule. TAZ may link events at the plasma membrane and cytoskeleton to nuclear transcription in a manner that can be regulated by 14-3-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.