|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence QIYPFVFESRKEIL, from C Terminus of the protein sequence according to NP_004856.|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-31760 detects TBP like protein TLP from human samples.
PA1-31760 has been successfully used in Western blot applications.
The PA1-31760 immunogen is: Peptide with sequence QIYPFVFESRKEIL, from C Terminus of the protein sequence according to NP_004856.
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that serves the same function as TBP and substitutes for TBP at some promoters that are not recognized by TFIID. It is essential for spermiogenesis and believed to be important in expression of developmentally regulated genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 21 kDa TBP-like protein; 21-kDA TBP-like protein; MGC:8389; MGC:9620; Second TBP of unique DNA protein; STUD; TATA box binding protein-like 1; TATA box binding protein-like protein; TATA box-binding protein-like protein 1; TATA box-binding protein-related factor 2; TBP-like 1; TBP-like factor; TBP-like protein 1; TBP-related factor 2; TBP-related protein; TLF; TLP; TRF2
Gene Aliases: 4732475G08; AW011832; AW491032; D18347; MGC:8389; MGC:9620; STD; STUD; TBPL1; TLF; TLP; TLP21; TRF2; TRP
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