PA5-29768 targets TBX2 in WB applications and shows reactivity with Human samples.
The PA5-29768 immunogen is recombinant fragment corresponding to a region within amino acids 98 and 338 of Human TBX2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.
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Protein Aliases: T-box protein 2; T-box transcription factor TBX2
Gene Aliases: TBX2
UniProt ID: (Human) Q13207
Entrez Gene ID: (Human) 6909