|Flow Cytometry (Flow)||0.2-1.0 ug/10^6 cells|
|Miscellaneous PubMed (MISC)||See 10 publications below|
|Tested Species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Armenian hamster / IgG|
|Immunogen||Affinity-purified DO-11.10 TCR|
|Excitation/Emission Profile||View spectra|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||4° C, do not freeze|
MA5-17653 targets TCR alpha/beta in FACS applications and shows reactivity with Mouse samples.
The MA5-17653 immunogen is affinity-purified DO-11.10 TCR.
The T cell antigen receptor (TCR) consists of a ligand-specific alpha/beta heterodimer non-covalently associated with five invariant chains including the CD3 gamma/delta/eta and zeta subunits, all of which are required for efficient surface expression. T cell activation through the TCR induces cellular differentiation and/or proliferation and the production of lymphokines and cytokines. Both the CD3 and TCR zeta subunits are proposed to be responsible for the intracellular signal transduction events.
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