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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human TDGF1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-15843 targets TDGF1 in WB applications and shows reactivity with Human samples.
The MA5-15843 immunogen is purified recombinant fragment of human TDGF1 expressed in E. Coli. .
This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects.The cripto gene is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. It could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.Tissue specificity: Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
CR, CRGF, CRIPTO, cripto-1 growth factor; cripto-1 growth factor; epidermal growth factor-like cripto protein CR1
CR; CRGF; CRIPTO; TDGF1