|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human, Mammal|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Human TFIIB eukaryotic transcription factor.|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
MA1-25431 detects TFIIB from human samples. MA1-25431 is expected to cross react with most mammalian TBPs due to sequence homology.
MA1-25431 has been successfully used in Western blot procedures.
The MA1-25431 immunogen is human TFIIB eukaryotic transcription factor.
This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: general transcription factor IIB; General transcription factor TFIIB; RNA polymerase II alpha initiation factor; RNA polymerase II transcription factor IIB; RP11-82K18.1; S300-II; TF2B; TFIIB; Transcription initiation factor IIB
Gene Aliases: BOS_3305; GTF2B; TF2B; TFIIB; XLTFIIB
Molecular Function: transcription factor
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