|Tested species reactivity||Human, Sheep|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||TGF-beta 1 from human platelets|
|Storage buffer||PBS, pH 7|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay dependent|
|Western Blot (WB)||1-10 ng/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Blocking Assay (BLOCK)||See 4 publications below|
MA1-21479 detects TGF beta in Human samples.
MA1-21479 has been successfully used in ELISA and Western Blot procedures.
MA1-21479 immunogen corresponds to TGF-beta 1 from human platelets.
TGF beta (Transforming Growth Factor beta) is a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Very late antigen-4 in CD18-independent neutrophil emigration during acute bacterial pneumonia in mice.
MA1-21479 was used in blocking/activating experiment to study the role of VLA-4 in CD18-independent neutrophil emigration induced by bacteria
|Tasaka S,Richer SE,Mizgerd JP,Doerschuk CM||American journal of respiratory and critical care medicine (166:53)||2002|
alpha(4)-integrin mediates neutrophil-induced free radical injury to cardiac myocytes.
MA1-21479 was used in blocking/activating experiment to investigate the mechanism of heart injury mediated by emigrated PMNs
|Poon BY,Ward CA,Cooper CB,Giles WR,Burns AR,Kubes P||The Journal of cell biology (152:857)||2001|
The hepatic inflammatory response after acetaminophen overdose: role of neutrophils.
MA1-21479 was used in blocking/activating experiment to test the role of accumulated neutrophils in liver damage
|Lawson JA,Farhood A,Hopper RD,Bajt ML,Jaeschke H||Toxicological sciences : an official journal of the Society of Toxicology (54:509)||2000|
Negative regulation of phagocytosis in murine macrophages by the Src kinase family member, Fgr.
MA1-21479 was used in blocking/activating experiment to investigate the role of Fgr for the modulation of macrophages phagocytosis
|Gresham HD,Dale BM,Potter JW,Chang PW,Vines CM,Lowell CA,Lagenaur CF,Willman CL||The Journal of experimental medicine (191:515)||2000|