This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
MA5-12736 targets Transglutaminase II in IF, IHC (P), IP, and WB applications and shows reactivity with Canine, Guinea Pig, Human, and Rabbit samples.
The MA5-12736 immunogen is purified guinea pig liver TGase II.
Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C polypeptide; C polypeptide, protein-glutamine-gamma-glutamyltransferase; Protein-glutamine gamma-glutamyltransferase 2; protein-glutamine-gamma-glutamyltransferase; TG(C); TGase C; TGase H; TGase-2; TGase-H; TGC; Tissue transglutaminase; transglutaminase 2; transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase); transglutaminase 2, C polypeptide; Transglutaminase C; Transglutaminase H; Transglutaminase-2
Gene Aliases: TG(C); TGC; TGM2
UniProt ID: (Human) P21980