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Product Details
66149-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2c
Class
Monoclonal
Type
Antibody
Clone
4G7D4
Immunogen
TIMM44 Fusion Protein Ag21389 (153-452 aa encoded by BC033628)
Conjugate
Form
Liquid
Concentration
0.77 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AKTAKQSAE SVSKGGEKLG RTAAFRALSQ GVESVKKEID DSVLGQTGPY RRPQRLRKRT EFAGDKFKEE KVFEPNEEAL GVVLHKDSKW YQQWKDFKEN NVVFNRFFEM KMKYDESDNA FIRASRALTD KVTDLLGGLF SKTEMSEVLT EILRVDPAFD KDRFLKQCEN DIIPNVLEAM ISGELDILKD WCYEATYSQL AHPIQQAKAL GLQFHSRILD IDNVDLAMGK MMEQGPVLII TFQAQLVMVV RNPKGEVVEG DPDKVLRMLY VWALCRDQDE LNPYAAWRLL DISASSTEQI L (153-452 aa encoded by BC033628)
Target Information
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mitochondrial import inner membrane translocase subunit TIM44; translocase of inner mitochondrial membrane 44 homolog; translocator of inner mitochondrial membrane 44; translocator of inner mitochondrial membrane 44; DNA segment, Chr 8, ERATO Doi 118, expressed
Gene Aliases: 0710005E20Rik; D8Ertd118e; MIMT44; TIM44; TIMM44
UniProt ID: (Human) O43615, (Mouse) O35857
Entrez Gene ID: (Human) 10469, (Mouse) 21856
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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