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FIGURE: 1 / 1
TIMM44 Antibody (MA5-55574) in WB
Western Blot analysis of various lysates using TIMM44 Recombinant Monoclonal Antibody (Product # MA5-55574) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
MA5-55574
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
8J1F10
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 10-240 of human TIM44.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
Immunogen Sequence: WCRCPRRCLG SGIQFLSSHN LPHGSTYQMR RPGGELPLSK SYSSGNRKGF LSGLLDNVKQ ELAKNKEMKE SIKKFRDEAR RLEESDVLQE ARRKYKTIES ETVRTSEVLR KKLGELTGTV KESLHEVSKS DLGRKIKEGV EEAAKTAKQS AESVSKGGEK LGRTAAFRAL SQGVESVKKE IDDSVLGQTG PYRRPQRLRK RTEFAGDKFK EEKVFEPNEE ALGVVLHKDS K
Target Information
This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mitochondrial import inner membrane translocase subunit TIM44; translocase of inner mitochondrial membrane 44 homolog; translocator of inner mitochondrial membrane 44
Gene Aliases: MIMT44; TIM44; TIMM44
UniProt ID: (Human) O43615, (Rat) O35094
Entrez Gene ID: (Human) 10469, (Rat) 29635
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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