|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||1-2 µg/ml|
|Immunohistochemistry (Paraffin) (IHC (P))||See 1 publications below|
|Immunohistochemistry (IHC)||See 31 publications below|
|Western Blot (WB)||See 4 publications below|
|Immunocytochemistry (ICC)||See 1 publications below|
|Tested Species reactivity||Rat, Bovine, Guinea pig, Human, Mouse, Rabbit|
|Published species reactivity||Rabbit , Rat , Bovine , Human , Mouse|
|Host / Isotype||Mouse / IgG2a, kappa|
|Immunogen||A synthetic peptide from the N-terminal region of human TIMP-2 protein|
|Storage buffer||PBS, pH 7.4, with 0.2% BSA|
|Contains||0.09% sodium azide|
|Storage conditions||4° C|
MA5-12207 targets TIMP-2 in IHC (P) and WB applications and shows reactivity with Bovine, Guinea Pig, Human, mouse, Rabbit, and Rat samples.
The MA5-12207 immunogen is a synthetic peptide from the N-terminal region of human TIMP-2 protein.
TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Collagenase inhibitor; CSC-21K; Metalloproteinase inhibitor 2; metalloproteinase inhibitor TIMP-2; testicular secretory protein Li 57; TIMP metallopeptidase inhibitor 2; TIMP-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase-2; Tissue inhibitor of metalloproteinases 2; tissue inhibitor of mettaloproteinase 2
Gene Aliases: BOS_19535; CSC-21K; D11Bwg1104e; DDC8; Timp-2; TIMP2
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