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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Recombinant Monoclonal |
Type |
Antibody |
Clone |
ARC0793 |
Immunogen |
A synthesized peptide derived from human TLE1 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.63 mg/mL |
Purification |
Protein A |
Storage buffer |
PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2849278 |
Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E(Sp1) homolog; Enhancer of split groucho-like protein 1; ESG1; Grg-1; Groucho-related protein 1; RP11-203D19.1; TLE 1; transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like; Transducin-like enhancer protein 1
Gene Aliases: C230057C06Rik; ESG; ESG1; Estm14; Grg-1; GRG1; TLE1; Tle4l
UniProt ID: (Human) Q04724, (Mouse) Q62440
Entrez Gene ID: (Human) 7088, (Mouse) 21885, (Rat) 362533
Molecular Function:
transcription cofactor
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