|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 1-100 of an N-terminal portion of human TLR10. [Swiss-Prot# Q9BXR5]|
|Purification||Antigen affinity chromatography|
|Storage buffer||citric acid, pH 7-8|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:500-1:1000|
|Western Blot (WB)||2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
The target sequence has 90% sequence homology with bovine.
Suggested positive control: antigen standard for TLR10 (transient overexpression lysate), Ramos whole cell extracts.
Toll-like receptors (TLRs) are membrane proteins on many cells involved with innate immunity such as macrophages, dendritic cells, neutrophils, mucosal epithelial cells, and endothelial cells. Ten mammalian TLRs have been identified and all have distinct specificities for microbial ligands. Upon recognition of a microbial product, TLRs initiate a signaling pathway to activate innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.