|Flow Cytometry (Flow)||1.0 ug/10^6 cells|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Excitation/Emission Profile||View spectra|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||4° C, do not freeze|
MA5-17724 targets CD282/TLR2/Toll-like Receptor 2 in FACS applications and shows reactivity with Human samples.
The MA5-17724 immunogen is human TLR2.
The TLR2 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This protein is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD282; TIL4; Toll-like Receptor 2; toll/interleukin 1 receptor-like 4; Toll/interleukin-1 receptor-like protein 4
Gene Aliases: CD282; TIL4; TLR2
UniProt ID: (Human) O60603
Entrez Gene ID: (Human) 7097
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.