|Tested species reactivity||Mouse|
|Host / Isotype||Rat / IgG2b|
|Storage buffer||PBS with 0.1% BSA|
|Contains||0.02% sodium azide|
|Storage Conditions||4° C|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:50|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-40048 detects TLR2 from mouse samples.
MA1-40048 has been successfully used in flow cytometry, immunoprecipitation, and immunofluorescence applications.
The MA1-40048 immunogen is mouse TLR2/CD282.
The TLR2 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This protein is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.