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|Tested species reactivity||Human|
|Published species reactivity||Pig|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Recombinant human TLR7 (aa451-500) purified from E. coli|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage Conditions||4°C or -20°C if preferred|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||1:1000 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In Western blot, this antibody detects a band at ~121 kDa in Ramos cell lysate.
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Production of tumor necrosis factor-alpha from porcine nucleus pulposus cells at various time points in cell culture under conditions of nutritional deficiency.
MA1-81963 was used in immunohistochemistry to investigate the changes of tumor necrosis factor alpha expression in pigs under starvation conditions
|Murata Y,Olmarker K,Larsson K,Takahashi K,Rydevik B||Cytokine (34:206)||2006|
Detection of monokines in paraffin-embedded tissues of pigs using polyclonal antibodies.
MA1-81963 was used in ELISA to investigate the reliability of antibodies for the measurement of monokines in paraffin-embedded pig tissues
|Salguero FJ,Mekonnen T,Ruiz-Villamor E,Sánchez-Cordón PJ,Gómez-Villamandos JC||Veterinary research (32:601)||2002|
Cellular changes and cytokine expression in the ilea of gnotobiotic piglets resulting from peroral Salmonella typhimurium challenge.
MA1-81963 was used in immunocytochemistry to investigate the changes of cytokine gene expression in piglets infected with Salmonella typhimurium
|Trebichavský I,Dlabac V,Reháková Z,Zahradnícková M,Splíchal I||Infection and immunity (65:5244)||1997|
Toll-like receptor 7; toll-like receptor 7-like
TLR7; TLR7-like; UNQ248/PRO285