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Alomone Labs, LTD
TMEM106B (extracellular) Polyclonal Antibody
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FIGURE: 1 / 5
TMEM106B (extracellular) Antibody (ANR-177-200UL) in IHC (F)
Expression of TMEM106B in mouse hippocampus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections with Anti-TMEM106B (extracellular) Antibody (#ANR-177) (1:600), followed by goat anti-rabbit-AlexaFluor-488. A. Staining in the hippocampal dentate gyrus region, showed TMEM106B immunoreactivity (green) in neurons (arrows). B. Pre-incubation of the antibody with TMEM106B (extracellular) B... View More
Product Details
ANR-177-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide EVIKELQEFYKDTYQK, corresponding to amino acid residues 114-129 of mouse CD9. Extracellular, 2nd loop.
Conjugate
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: EVIKELQEFYKDTYQK
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Transmembrane protein 106B (TMEM106B) is a single-pass transmembrane protein that is thought to be a novel risk factor for frontotemporal lobar degeneration (FTLD), a group of clinically, pathologically and genetically heterogeneous disorders associated with atrophy in the frontal lobe and temporal lobe of the brain. The actual role of TMEM106B, and that of the closely related protein TMEM106A are still undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Transmembrane protein 106B
Gene Aliases: 2310036D22Rik; 5830455K21Rik; 6430519M21Rik; AI428776; AI661344; LRRGT00101; TMEM106B
UniProt ID: (Human) Q9NUM4, (Mouse) Q80X71, (Rat) Q6AYA5
Entrez Gene ID: (Human) 54664, (Mouse) 71900, (Rat) 312132
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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