|Western Blot (WB)||Assay Dependent|
|Host / Isotype||Mouse / IgG1, kappa|
|Immunogen||Recombinant human TNF alpha.|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
The M303 anti-TNF Alpha antibody (clone 2TNF-H34A) has successfully been paired as the coating antibody in a sandwich ELISA with detection antibody M302B (biotinylated conjugate of clone 2TNF-H33).
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: APC1 protein; Cachectin; TNF superfamily, member 2; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; TNF-alpha; Tumor necrosis factor; tumor necrosis factor alpha; tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha
Gene Aliases: DIF; TNF; TNF-alpha; TNFA; TNFSF2; TNLG1F
UniProt ID: (Human) P01375
Entrez Gene ID: (Human) 7124
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.