|Tested species reactivity||Human|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Fusion protein corresponding to the extracellular domain (residues 39-200) of human TNFRSF14, fused to the Fc portion of human IgG1.|
|Purification||Size-exclusion - Gel filtration|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25844 detects TNFRSF14 from human samples.
MA1-25844 has been successfully used in immunofluorescence, and immunoprecipitation procedures.
The MA1-25844 immunogen is a fusion protein corresponding to the extracellular domain (residues 39-200) of human TNFRSF14, fused to the Fc portion of human IgG1.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex virus (HSV) entry. Binding of HSV viral envelope glycoprotein D (gD) to this receptor protein has been shown to be part of the viral entry mechanism. The cytoplasmic region of this receptor was found to bind to several TRAF family members, which may mediate the signal transduction pathways that activate the immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.