|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the TOB.|
|Purification||Ammonium sulfate precipitation|
|Contains||0.08% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control for this product is HeLa cell lysate.
TOB does not contain either SH2 or SH3 domains but is homologous with the N terminus of the anti-proliferative BTG-1 protein. Like BTG-1, TOB when exogenously expressed, is able to suppress the growth of NIH3T3 cells. This growth suppression is hindered by the presence of kinase-active p185erbB2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.