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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Synthetic peptide corresponding to residues 1-20 of human TRAIL Receptor 1.|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||2-4 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA1-25373 detects TRAIL Receptor 1 from human samples.
MA1-25373 has been successfully used in Western blot procedures.
The MA1-25373 immunogen is a synthetic peptide corresponding to residues 1-20 of human DR4.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
APO2; CD261; cytotoxic TRAIL receptor; death receptor 4; DR4; MGC9365; TNF-related apoptosis-inducing ligand receptor 1; TRAIL receptor 1; TRAIL-R1; TRAILR-1; TRAILR1; tumor necrosis factor receptor superfamily member 10a variant 2; tumor necrosis factor receptor superfamily, member 10a
APO2; CD261; DR4; TNFRSF10A; TRAILR-1; TRAILR1