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FIGURE: 1 / 1
TRIP10 Antibody (MA5-55410) in WB
Western Blot analysis of various lysates using TRIP10 Recombinant Monoclonal Antibody (Product # MA5-55410) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
Product Details
MA5-55410
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
6C3I3
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cip4.
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
Immunogen Sequence: MDWGTELWDQ FEVLERHTQW GLDLLDRYVK FVKERTEVEQ AYAKQLRSLV KKYLPKRPAK DDPESKFSQQ QSFVQILQEV NDFAGQRELV AENLSVRVCL
Target Information
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cdc42 interacting protein-4; Cdc42-interacting protein 4; hSTP; Protein Felic; Salt tolerant protein; salt tolerator; Thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
Gene Aliases: AI646975; CIP4; HSTP; STOT; STP; TRIP-10; TRIP10
UniProt ID: (Human) Q15642, (Mouse) Q8CJ53
Entrez Gene ID: (Human) 9322, (Mouse) 106628
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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