This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse TROP-2/TACSTD2.
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cell surface glycoprotein Trop-2; GA733; lymphocyte antigen 97; TACD2; Tumor-associated calcium signal transducer 2; tunor-associated calcium signal transducer 2
Gene Aliases: C80403; EGP-1; GA733-1; Ly97; Tacstd2; TROP2
UniProt ID: (Mouse) Q8BGV3
Entrez Gene ID: (Mouse) 56753
Molecular Function: receptor