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|Tested species reactivity||Human|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from the 4th cytoplasmic loop of human TRPC6 conjugated to an immunogenic carrier protein|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:300-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Glycerol (1:1) may be added for additional stability.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
focal segmental glomerulosclerosis 2; hTrp-3; hTRP7; likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7; putative capacitative calcium channel; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; transient receptor potential cation channel, subfamily C, member 6; transient receptor potential cation channel, subfamily C, member 7; transient receptor protein 3; transient receptor protein 6; transient receptor protein 7; TRP-6; TRP-7; Trpc3; Trpc6; Trpc7
FSGS2; SCA41; TRP3; TRP6; TRP7; TRPC3; TRPC6; TRPC7