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ZNF289 (zinc finger protein 289), also known as ARFGAP2 (ADP-ribosylation factor GTPase activating protein 2), IRZ, Zfp289 or Nbla10535, functions as a GTPase-activating protein (GAP) for ARF family proteins. Localizing to the cytoplasmic side of the Golgi apparatus, ZNF289 contains one ARF-GAP domain and is found associated with COP-I-coated vesicles.
Protein Aliases: Tsc-22-like protein THG-1; TSC22 domain family protein 4; TSC22 domain family, member 4; TSC22-related-inducible leucine zipper protein 2
Gene Aliases: THG-1; THG1; TILZ2; TSC22D4
UniProt ID: (Human) Q9Y3Q8
Entrez Gene ID: (Human) 81628