Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
This product was used in an Indirect ELISA.
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa, are homologous but not identical. The alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost all eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-tubulin 1; Testis-specific alpha-tubulin; Tubulin alpha; Tubulin alpha-1 chain; Tubulin alpha-4A chain; Tubulin H2-alpha; tubulin, alpha 1 (testis specific); tubulin, alpha 4a
Gene Aliases: ALS22; H2-ALPHA; TUBA1; TUBA4A
UniProt ID: (Human) P68366
Entrez Gene ID: (Human) 7277
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support