This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-tubulin 8; Tubulin alpha chain-like 2; Tubulin alpha-8 chain; tubulin, alpha 8
Gene Aliases: TUBA8; TUBAL2
Molecular Function: tubulin