|Tested species reactivity||Yeast|
|Host / Isotype||Mouse / IgG|
|Immunogen||Recombinant protein corresponding to the residues 1-200 of yeast TUP1 protein.|
|Contains||0.08% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||5-10 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
A suggested positive control for this product is Mav108 cells expressing recombinant TUP1 protein.
TUP 1 and SSN6 are involved in repression of several diverse families of genes in yeast, including cell type-specific genes regulated by the alphga2 and a1/alpha2 repressors. Ssn6-Tupl interacts with class I histone deacetylases required for repression, and rfecrfuitment of yeast Tuplp-Ssn6p repressor is associated with localized decreases in histone acetylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.