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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG2b|
|Immunogen||Purified recombinant fragment of human TWIST1 (amino acids: 9-74) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17195 targets TWIST1 in WB applications and shows reactivity with Human samples.
The MA5-17195 immunogen is purified recombinant fragment of human TWIST1 (amino acids: 9-74) expressed in E. Coli.
MA5-17195 detects TWIST1 which has a predicted molecular weight of approximately 21kDa.
Basic helix-loop-helix (bHLH) transcription factors have been implicated in cell lineage determination and differentiation. The protein encoded by this gene is a bHLH transcription factor and shares similarity with another bHLH transcription factor, Dermo1. The strongest expression of this mRNA is in placental tissue; in adults, mesodermally derived tissues express this mRNA preferentially. Mutations in this gene have been found in patients with Saethre-Chotzen syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
B-HLH DNA binding protein; class A basic helix-loop-helix protein 38; H-twist; twist basic helix-loop-helix transcription factor 1; twist homolog 1; TWIST homolog of drosophila
ACS3; BHLHA38; BPES2; BPES3; CRS; CRS1; CSO; SCS; TWIST; TWIST1