|Western Blot (WB)||0.2-0.6 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (EQKDSDNYRVFER) corresponding to the internal amino acids of TXNDC4|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1L and ERO1LB in the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum resident protein 44; endoplasmic reticulum resident protein 44 kDa; ER protein 44; ERP44; KIAA0573; OTTHUMP00000063799; protein disulfide isomerase family A, member 10; thioredoxin domain containing 4 (endoplasmic reticulum); Thioredoxin domain-containing protein 4; TXNDC4
Gene Aliases: ERP44; KIAA0573; PDIA10; TXNDC4; UNQ532/PRO1075
UniProt ID: (Human) Q9BS26
Entrez Gene ID: (Human) 23071
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