Immunogen sequence: NHISSLNWGY RLSLREKAVA YVNSYGEFVE HHKIKATNKK GQETYYTAAQ
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted homology: Dog: 86%; Guinea Pig: 77%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 86%; Rabbit: 85%; Rat: 79%; Zebrafish: 79%
Displays thioredoxin reductase, glutaredoxin and glutathione reductase activities. Catalyzes disulfide bond isomerization. Promotes disulfide bond formation between GPX4 and various sperm proteins and may play a role in sperm maturation by promoting formation of sperm structural components.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Thioredoxin and glutathione reductase; thioredoxin glutathione reductase; thioredoxin reductase 2; Thioredoxin reductase 3; Thioredoxin reductase TR2; TXNRD3
Gene Aliases: TGR; TR2; TRXR3; TXNRD3
UniProt ID: (Human) Q86VQ6
Entrez Gene ID: (Human) 114112
Molecular Function: reductase